“Inform Diagnostics’ precision and laboratory excellence have earned the trust of clinicians and enhanced patient care,” says Sriram Venkataraman, Avista Partner. During Avista’s ownership period, Inform Diagnostics executed on a host of corporate and growth initiatives, including the appointments of numerous senior team members, enhanced financial flexibility to drive corporate growth, and strengthened compliance policies and procedures. Shortly thereafter, Inform Diagnostics grew its capabilities via the acquisition of Therapath, a neuropathology laboratory based in New York and the expansion of its Newton, Massachusetts facility. In 2017, Avista’s Fund IV carved out Inform Diagnostics from Miraca Life Sciences and worked with the newly recruited management team to create a standalone company. The company currently provides services to approximately 1,300 clients who represent over 2,700 physicians.įulgent Genetics originally announced its definitive agreement to acquire Inform Diagnostics for approximately $170 million on April 18, 2022. Inform Diagnostics’ offerings include gastrointestinal pathology, dermatopathology, urologic pathology, and hematopathology, among other laboratory functions. These tools will help monitor the phytosanitary status of rice seeds to avoid the dissemination of Pantoea spp.Avista Capital Partners, a private equity firm focused on healthcare, closed on the sale of pathology laboratory Inform Diagnostics to Fulgent Genetics. Two diagnostic tools have been therefore developed: one that detects all known Pantoea species and another one that is specific for P. The goal of this work was to overcome the above difficulties and facilitate a quick and cost-effective diagnosis of the bacteria in rice leaves and paddy fields. However, LAMP has so far not been applied to rice/ Pantoea spp., neglected pathosystems that are wide-spread and important in Africa (12, 14). It has been used for highly specific and sensitive DNA amplification to detect various pathogens, including viruses, bacteria, protozoa and fungi. LAMP has several advantages, such as portability, simplicity and cost-efficiency because the reaction can be carried out in a water bath or heating block. The results of LAMP reactions can be detected without electrophoretic separation but by visualization of turbidity, fluorescence or a color change thanks to a metal ion indicator. The technique uses the thermostable Bst DNA polymerase for reliable and fast polymerization and operates under isothermal conditions at relatively high temperature. Isothermal loop-mediated amplification (LAMP) is a relatively simple technique that facilitates rapid amplification of DNA and has a high level of sensitivity and specificity at low cost. However, their use is complex, time consuming, expensive and cannot be deployed outside the laboratory. A semi-selective medium for their isolation and identification has also been developed. New diagnostic tools have been developed, such as simplex and multiplex PCR schemes able of identifying the three major Pantoea species affecting rice plants. Thus, measures need to be taken to limit the pathogens' dispersion and robust diagnostic tools are required for rapid and cheap diagnosis that can be used in the field as well as in routine screening of seed lots. are seed-transmitted and thus pose a significant threat to interstate and continental seed exchanges. Collectively, they cause various diseases and symptoms, such as leaf blight and dieback, red streak, black spot, necrosis, bacterial spot, tumors, rot center, stem necrosis, leaf rot, decay of seed and Stewart's wilt. stewartii on rice plants and seeds in Sub-Saharan Africa. wallisii, have been widely reported as plant pathogens, ,, with P. The Pantoea genus is composed of several species characterized by their ubiquity and versatility in their interactions with living organisms and the environment.
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